The organization of cells into epithelial layers is a fundamental structural context for understanding animal development and evolution. The Gibson lab employs a wide range of technical approaches to elucidate the cellular and molecular mechanisms that direct the growth of epithelial tissue and coordinate epithelial cell mitosis with the maintenance of polarized tissue architecture in vivo.
Our research plan is balanced across two model organisms: the fruit fly, Drosophila melanogaster, and the starlet sea anemone, Nematostella vectensis. We leverage Drosophila’s highly developed genetic toolkit to functionally interrogate the regulation of epithelial cell shape and proliferation while capitalizing on Nematostella’s advantageous phylogenetic position to develop a comparative and evolutionary perspective on epithelial growth, patterning, and morphogenesis.
We are currently extending several lines of questioning in two principle domains:
Projects in the Gibson lab are driven by members’ research interests; visit the People page to see what everyone's up to right now.
1000 East 50th Street
Kansas City, MO 64110