Stowers
Microscopy Center
Publications (Since 2010)

44. Burns S, Avena JS, Unruh JR, Yu Z, Smith SE, Slaughter BD, Winey M, Jaspersen SL. Structured illumination with particle averaging reveals novel roles for yeast centrosome components during duplication [published ahead of print September 16 2015]. eLife. 2015;4. Pubmed

43. De Kumar B, Parrish ME, Slaughter BD, Unruh JR, Gogol M, Seidel C, Paulson A, Li H, Gaudenz K, Peak A, McDowell W, Fleharty B, Ahn Y, Lin C, Smith E, Shilatifard A, Krumlauf R. Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells. Genome Res. 2015;25:1229-1243. Pubmed

42. Lake CM, Nielsen RJ, Guo F, Unruh JR, Slaughter BD, Hawley RS. Vilya, a component of the recombination nodule, is required for meiotic double-strand break formation in Drosophila. eLife. 2015;4. doi: 10.7554/eLife.08287. Pubmed

41. Romero-Carvajal A, Navajas Acedo J, Jiang L, Kozlovskaja-Gumbriene A, Alexander R, Li H, Piotrowski T. Regeneration of Sensory Hair Cells Requires Localized Interactions between the Notch and Wnt Pathways [published ahead of print July 21 2015]. Dev Cell. 2015. Pubmed

40. Thi-Kim Vu H, Rink JC, McKinney SA, McClain M, Lakshmanaperumal N, Alexander R, Sánchez Alvarado A. Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ. eLife. 2015;4: doi: 10.7554/eLife.07405. Pubmed

39. Weems JC, Slaughter BD, Unruh JR, Hall SM, McLaird MB, Gilmore JM, Washburn MP, Florens L, Yasukawa T, Aso T, Conaway JW, Conaway RC. Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses. J Biol Chem. 2015;290:15030-15041. Pubmed

38. Adler CE, Seidel CW, McKinney SA, Sanchez Alvarado A. Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria. eLife. 2014;3:e02238. Pubmed

37. Avena JS, Burns S, Yu Z, Ebmeier CC, Old WM, Jaspersen SL, Winey M. Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1. PLoS Genet. 2014;10:e1004666. Pubmed

36. Chen J, Smoyer CJ, Slaughter BD, Unruh JR, Jaspersen SL. The SUN protein Mps3 controls Ndc1 distribution and function on the nuclear membrane. J Cell Biol. 2014;204:523-539. Pubmed

35. Collins KA, Unruh JR, Slaughter BD, Yu Z, Lake CM, Nielsen RJ, Box KS, Miller DE, Blumenstiel JP, Perera AG, Malanowski KE, Hawley RS. Corolla is a novel protein that contributes to the architecture of the synaptonemal complex of Drosophila. Genetics. 2014;198:219-228. Pubmed

34. Harris B, Bose T, Lee KK, Wang F, Lu S, Ross RT, Zhang Y, French SL, Beyer AL, Slaughter BD, Unruh JR, Gerton JL. Cohesion promotes nucleolar structure and function. Mol Biol Cell. 2014;25:337-346. Pubmed

33. Hollopeter G, Lange JJ, Zhang Y, Vu TN, Gu M, Ailion M, Lambie EJ, Slaughter BD, Unruh JR, Florens L, Jorgensen EM. The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex. eLife. 2014;3:e03648. Pubmed

32. Ikmi A, McKinney SA, Delventhal KM, Gibson MC. TALEN and CRISPR/Cas9-mediated genome editing in the early-branching metazoan Nematostella vectensis. Nat Commun. 2014;5:5486, doi10.1038/ncomms6486. Pubmed

31. Zhou C, Slaughter BD, Unruh JR, Guo F, Yu Z, Mickey K, Narkar A, Ross RT, McClain M, Li R. Organelle-based aggregation and retention of damaged proteins in asymmetrically dividing cells. Cell. 2014;159:530-542. Pubmed

30. Bonner AM, Hughes SE, Chisholm JA, Smith SK, Slaughter BD, Unruh JR, Collins KA, Friederichs JM, Florens L, Swanson SK, Pelot MC, Miller DE, Washburn MP, Jaspersen SL, Hawley RS. Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains. PNAS. 2013;110:E1222-1231. Pubmed

29. Lange JJ, Wood CJ, Marshall WA, Maddera LE, Yu QE, Bradford WD, Slaughter BR, Unruh JR, Wiegraebe W. Correction of bleaching artifacts in high content fluorescence correlation spectroscopy (HCS-FCS) data. Proceedings SPIE. 2013;859006. doi:10.1117/12.2005205.

28. Nakajima Y, Meyer EJ, Kroesen A, McKinney SA, Gibson MC. Epithelial junctions maintain tissue architecture by directing planar spindle orientation. Nature. 2013;500:359-362. Pubmed

27. Slaughter BD, Unruh JR, Das A, Smith SE, Rubinstein B, Li R. Non-uniform membrane diffusion enables steady-state cell polarization via vesicular trafficking. Nat Commun. 2013;4:1380. Pubmed

26. Smith SE, Rubinstein B, Mendes Pinto I, Slaughter BD, Unruh JR, Li R. Independence of symmetry breaking on Bem1-mediated autocatalytic activation of Cdc42. J Cell Biol. 2013;202:1091-1106. Pubmed

25. Yi K, Rubinstein B, Unruh JR, Guo F, Slaughter BD, Li R. Sequential actin-based pushing forces drive meiosis I chromosome migration and symmetry breaking in oocytes. J Cell Biol. 2013;200:567-576. Pubmed

24. Bose T, Lee KK, Lu S, Xu B, Harris B, Slaughter B, Unruh J, Garrett A, McDowell W, Box A, Li H, Peak A, Ramachandran S, Seidel C, Gerton JL. Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells. PLoS Genet. 2012;8:e1002749. Pubmed

23. Das A, Slaughter BD, Unruh JR, Bradford WD, Alexander R, Rubinstein B, Li R. Flippase-mediated phospholipid asymmetry promotes fast Cdc42 recycling in dynamic maintenance of cell polarity. Nat Cell Biol. 2012;14:304-310. Pubmed

22. Friederichs JM, Gardner JM, Smoyer CJ, Whetstine CR, Gogol M, Slaughter BD, Jaspersen SL. Genetic analysis of Mps3 SUN domain mutants in Saccharomyces cerevisiae reveals an interaction with the SUN-like protein Slp1. G3 (Bethesda). 2012;2:1703-1718. Pubmed

21. Ghosh S, Gardner JM, Smoyer CJ, Friederichs JM, Unruh JR, Slaughter BD, Alexander R, Chisholm RD, Lee KK, Workman JL, Jaspersen SL. Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization. Mol Biol Cell. 2012;23:2546-2559. Pubmed

20. Ma L, Qiu Q, Gradwohl S, Scott A, Yu EQ, Alexander R, Wiegraebe W, Yu CR. Distributed representation of chemical features and tunotopic organization of glomeruli in the mouse olfactory bulb. PNAS. 2012;109:5481-5486. Pubmed

19. Ma L, Qiu Q, Gradwohl S, Scott A, Yu EQ, Alexander R, Wiegraebe W, Yu CR. Reply to Yablonka et al.: Parity in Data Processing is Essential in Correlation Analyses. PNAS. 2012;109:E2918-E2910.

18. Majumdar A, Cesario WC, White-Grindley E, Jiang H, Ren F, Khan MR, Li L, Choi EM, Kannan K, Guo F, Unruh J, Slaughter B, Si K. Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory. Cell. 2012;148:515-529. Pubmed

17. Mendes Pinto I, Rubinstein B, Kucharavy A, Unruh J, Li R. Actin Depolymerization Drives Actomyosin Ring Contraction during Budding Yeast Cytokinesis. Dev Cell. 2012;22:1247-1260. Pubmed

16. Rubinstein B, Slaughter BD, Li R. Weakly nonlinear analysis of symmetry breaking in cell polarity models. Phys Biol. 2012;9:045006. Pubmed

15. Shivaraju M, Unruh JR, Slaughter BD, Mattingly M, Berman J, Gerton JL. Cell-cycle-coupled structural oscillation of centromeric nucleosomes in yeast. Cell. 2012;150:304-316. Pubmed

14. Suraneni P, Rubinstein B, Unruh JR, Durnin M, Hanein D, Li R. The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration. J Cell Biol. 2012;197:239-251. Pubmed

13. Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV, Jr., Mak HY. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. J Cell Biol. 2012;198:895-911. Pubmed

12. Xu XP, Rouiller I, Slaughter BD, Egile C, Kim E, Unruh JR, Fan X, Pollard TD, Li R, Hanein D, Volkmann N. Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors. EMBO J. 2012;31:236-247. Pubmed

11. Friederichs JM, Ghosh S, Smoyer CJ, McCroskey S, Miller BD, Weaver KJ, Delventhal KM, Unruh J, Slaughter BD, Jaspersen SL. The SUN Protein Mps3 Is Required for Spindle Pole Body Insertion into the Nuclear Membrane and Nuclear Envelope Homeostasis. PLoS Genet. 2011;7:e1002365. Pubmed

10. Gardner JM, Smoyer CJ, Stensrud ES, Alexander R, Gogol M, Wiegraebe W, Jaspersen SL. Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z. J Cell Biol. 2011;193:489-507. Pubmed

9. Hao Y, Xu N, Box A, Schaefer L, Kannan K, Zhang Y, Florens L, Seidel C, Washburn M, Wiegraebe W, Mak HY. Nuclear cGMP-Dependent Kinase Regulates Gene Expression via Activity-Dependent Recruitment of a Conserved Histone Deacetylase Complex. PLoS Genet. 2011;7:e1002065. Pubmed

8. Hughes SE, Beeler JS, Seat A, Slaughter BD, Unruh JR, Bauerly E, Matthies HJ, Hawley RS. Gamma-Tubulin Is Required for Bipolar Spindle Assembly and for Proper Kinetochore Microtubule Attachments during Prometaphase I in Drosophila Oocytes. PLoS Genet. 2011;7:e1002209. Pubmed

7. Parrish M, Unruh J, Krumlauf R. BAC modification through serial or simultaneous use of CRE/Lox technology. J Biomed Biotechnol. 2011;2011:924068. Pubmed

6. Wood C, Huff J, Marshall W, Yu EQ, Unruh J, Slaughter B, Wiegraebe W. Fluorescence correlation spectroscopy as tool for high-content-screening in yeast (HCS-FCS). Proceedings of the SPIE. 2011;7905, 79050H.

5. Yi K, Unruh JR, Deng M, Slaughter BD, Rubinstein B, Li R. Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. Nat Cell Biol. 2011;13:1252-1258. Pubmed

4. Zhou C, Slaughter BD, Unruh JR, Eldakak A, Rubinstein B, Li R. Motility and segregation of hsp104-associated protein aggregates in budding yeast. Cell. 2011;147:1186-1196. Pubmed

3. He J, Ma L, Kim S, Schwartz J, Santilli M, Wood C, Durnin MH, Yu CR. Distinct Signals Conveyed to Pheromone Concentrations to the Mouse Vomeronasal Organ. J Neurosci. 2010;30:7473-7483. Pubmed

2. Kulesa PM, Teddy JM, Smith M, Alexander R, Cooper CH, Lansford R, McLennan R. Multispectral fingerprinting for improved in vivo cell dynamics analysis. BMC Dev Biol. 2010;10:101. Pubmed

1. Lutes AA, Neaves WB, Baumann DP, Wiegraebe W, Baumann P. Sister chromosome pairing maintains heterozygosity in parthenogenetic lizards. Nature. 2010;464:283-286. Pubmed

Reviews, Commentaries, Chapters or Books (Last 5 Years)

5. Smith SE, Slaughter BD, Unruh JR. Imaging methodologies for systems biology. Cell Adh & Migr. 2014;8:468-477.

4. Unruh JR, Slaughter BD, Li R. Quality Control: Putting Protein Aggregates in a Bind. Curr Biol. 2013;23:R74-R76. Pubmed

3. Slaughter BD, Unruh JR, Li R. Fluorescence fluctuation spectroscopy and imaging methods for examination of dynamic protein interactions in yeast. Methods Mol Biol. 2011;759:283-306. Pubmed

2. Slaughter BD, Li R. Toward Quantitative "In Vivo Biochemistry" with Fluorescence Fluctuation Spectroscopy. Mol Biol Cell. 2010;21:4306-4311. Pubmed

1. Slaughter BD, Smith SE, Li R. Symmetry breaking in the life cycle of the budding yeast. Cold Spring Harbor Perspect Biol. 2010;1:a003384. Pubmed