Stowers Institute for Medical Research
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Deeper into the MudPit

mudpit steps Sample Prep Digestion Multidimensional Chromatography Tandem Mass Spectrometry Database Matching Data Analysis Default

Mass Spectrometry

Mass Spectrometers @ SIMR
Type of tandem mass spectrometer used depends on project goals

Linear ion trap (LTQ) :
  1. Protein identification
  2. Label-free quantitation


Hybrid LTQ-Orbitrap :
  1. High resolution PTMs
  2. Quantitation (isotopic labeling)

Hybrid LTQ-Velos-Orbitrap-ETD:

LTQ Velos Orbitrap

Hybrid LTQ-Orbitrap Applications