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AHMET KARABULUT
Predoctoral Researcher
RESEARCH SUMMARY
My research focuses on the mechanism of cell specification and renewal in the highly regenerative model organism, Nematostella vectensis. I am studying how highly complex cell types are derived and continuously renewed from a progenitor. The ability to investigate the evolutionally conserved programs for cell specification and renewal in vivo can provide significant impact in regenerative biology research.

EDUCATION
MS Molecular Genetics, University of Cincinnati (2009)
BS  Molecular Biology and Genetics, Istanbul Technical University  (2004)

SELECTED PUBLICATIONS:
Electroporation of short hairpin RNAs for rapid and efficient gene knockdown in the starlet sea anemone, Nematostella vectensis.
Karabulut, A., He, S., Chen, C. , McKinney, S.A., Gibson, M.C.(2019)
Developmental Biology
PubMed

Antibiotic Compounds and Compositions and Methods for Identification Thereof
Smith, GR, Amundsen, SK, Karabulut AC, Bannister TD, Nair, RN.
U. S. Prov. Patent Application 61/613367 April 20, 2012 (Patent Application)

Small-molecule inhibitors of bacterial AddAB and RecBCD helicase-nuclease DNA repair enzymes.
Amundsen, S. K., Spicer, T., Karabulut, A. C., Londoño, L. M., Eberhardt, C., Fernandez Vega V, Bannister, T. D., Hodder, P., and Smith, G. R. (2012)
ACS Chemical Biology 7, 879-891.
PubMed

A Novel Dual Inhibitor of Bacterial AddAB and RecBCD Helicase-nucleaseDNA Repair Enzymes.
Bannister, T. D., Nair, R., Spicer, T., Fernandez Vega, V., Eberhart, C., Mercer, B. A., Cameron M., Schurer, S., Amundsen, S. K., Karabulut, A., Londoño, L. M., Smith, G. R., and Hodder, P.  (2013).
ML328: In Probe Reports from the NIH Molecular Libraries Program (Bethesda, MD)
PubMed

Anaerobic killing of mucoid Pseudomon asaeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions.
Yoon, S.S., Coakley, R., Lau,G.W., Lymar, S.V., Gaston, B., Karabulut, A.C., Hennigan, R.F., Hwang, S.H., Buettner, G., Schurr,M.J., Mortensen, J,E,. Burns, J.L., Speert, D., Boucher, R.C, and Hassett, D.J.(2006)
Journal of Clinical Investigation 116, 436-446.
PubMed

Two-pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration.
Yoon, S.S., Karabulut, A.C., Lipscomb, J.D., Hennigan, R.F., Lymar, S.V., Groce, S.L., Herr, A.B., Howell,M.L., Kiley, P.J., Schurr, M.J., Gaston, B., Choi, K.Y., Schweizer, H.P., andHassett, D.J. (2007)
EMBO Journal 26, 3662-3672.
PubMed