The laboratory of Linheng Li mainly focuses on the hematopoietic and intestinal systems to study stem cell development. The hematopoietic system (led by L. Li) facilitates functional characterization of stem cells, as bone marrow transplantation experiments can be readily performed. The intestinal system (led by Senior Research Specialist Xi He) has a well-organized developmental architecture in which stem cell marking and lineage tracing can be used to investigate stem cell behavior.