Epithelial cell biology - Coordinating mitosis and morphogenesis during animal development

Epithelial cell biology - Coordinating mitosis and morphogenesis during animal development

WHAT WE DO

The organization of cells into epithelial layers is the fundamental structural context for understanding animal development and evolution.  The Gibson lab employs a wide range of technical approaches to elucidate the cellular and molecular mechanisms that direct the growth of epithelial tissue and coordinate epithelial cell mitosis with the maintenance of polarized tissue architecture in vivo.

Our research plan leverages  two model organisms: the fruit fly, Drosophila melanogaster, and the starlet sea anemone, Nematostella vectensis.  We take advantage of Drosophila’s highly developed genetic toolkit to functionally interrogate the regulation of epithelial cell shape and proliferation while capitalizing on Nematostella’s advantageous phylogenetic position to develop a comparative and evolutionary perspective on epithelial growth, patterning, and morphogenesis.

RESEARCH HIGHLIGHTS

LAB MEMBERS

Matt Gibson
Principal Investigator
Takuya Akiyama
Research Scientist
Eric Hill
Postdoctoral Research Associate
Elizabeth Bauerly
Predoctoral Researcher
Cheng-Yi Chen
Predoctoral Researcher
Ahmet Karabulut
Predoctoral Researcher
Lacey Ellington
Research Technician II
Subu Ramanathan
Postdoctoral Research Associate
Shuonan He
Predoctoral Researcher
Zachary Lee
Predoctoral Researcher
Ruohan Zhong
Predoctoral Researcher
Abby Dreyer
Administrative Assistant

Alumni

JOIN THE LAB

We’re always interested in finding motivated researchers to join the lab.

If you are interested in a research opportunity, please email Matt.

CONTACT

Matt Gibson
Stowers Institute for Medical Research
1000 East 50th Street, Room 285A,
Kansas City, MO 64110
(816) 926-4073
mg2@stowers.org