María Angélica grew up in Mexico and had the opportunity to be an undergraduate at the most amazing Genomic Program at the National Autonomous University of Mexico (UNAM). For her undergraduate research, she joined the Rosenberg Lab at Baylor College of Medicine where she studied genes that when overexpressed cause DNA damage in E. coli. She joined the Stowers Institute program and decided to join SaraH Zanders’ lab to understand meiotic drive in fission yeast. Maria is now working as a postdoctoral fellow in Andrew Murray's lab at Harvard University. In her free time, she likes reading sci-fi books and running.
Atypical meiosis can be adaptive in outcrossed S. pombe due to wtf meiotic drivers.
Bravo Nunez MA, Sabbarini IM, Eide LE, Unckless RL, Zanders SE. eLife. 2020;9:e57936. doi: 57910.57554/eLife.57936. Dramatically diverse S. pombe wtf meiotic drivers all display high gamete-killing efficiency.
Bravo Núñez M.A., Sabbarini, I.M., Eickbush M.T., Liang, Y., Lange J.J., Kent, A.M., Zanders S.E. PLoS Genet. 2020; 16 (2), e1008350.
A suppressor of a wtf poison-antidote meiotic driver acts via mimicry of the driver's antidote.
Bravo Núñez M.A., Lange J.J., Zanders S.E. PLoS Genet. 2018;14(11):e1007836.
The transcription fidelity factor GreA impedes DNA break repair
Sivaramakrishnan, P., Sepúlveda, L.A., Halliday, J.A., Liu, J., Bravo Núñez, M.A., Golding, I., Rosenberg, S.M., and Herman, C. Nature,
wtf genes are prolific dual poison-antidote meiotic driver.
Nuckolls N.L., Bravo Núñez M.A., Eickbush M.T., Young J.M., Lange J.J., Yu J.S., Smith G.R., Jaspersen S.L., Malik H.S., Zanders S.E. eLife
.2017; 6:e26033Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli.
Jessica M. Moore, David Magnan, Ana K. Mojica, María Angélica Bravo Núñez, David Bates, Susan M. Rosenberg, P. J. Hastings. GENETICS
December 1, 2015 vol. 201 no. 4 1349-1362; DOI: 10.1534/genetics.115.178970An ultra-dense library resource for rapid deconvolution of mutations that cause phenotypes in Escherichia coli.
Ralf B Nehring, Franklin Gu, Hsin-Yu Lin, Janet L Gibson, Martin J Blythe, Ray Wilson, María Angélica Bravo Núñez, PJ Hasting, Edward J Louis, Ryan L Frisch, James Hu, Susan M Rosenberg. Nucleic Acids Res.
2016 Mar 18; 44(5):e41. doi: 10.1093/nar/gkv1131How a Large Gene Network Couples Mutagenic DNA Break Repair to Stress in Escherichia Coli. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria.
Rogers, E., Hastings, P.J., Bravo Nuñez, M. A., Rosenberg, S. M. (2016). John Wiley & Sons, Inc.
: 570-576Double-Strand-Break Repair, Mutagenesis, and Stress. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria.
Rogers, E., R. Correa, R., Barreto, B., Bravo Núñez, M.A., Minnick, P.J., Vera Crus, D., Xia, J., Hasting, P.J., Rosenberg, S. M. (2016). John Wiley & Sons, Inc