Research Technician III
Michael Eickbush grew up in Penfield, New York, a town just outside of Rochester. Having always enjoyed science, he studied Chemistry at the University at Buffalo. As an undergraduate, during the summers he worked as a programmer in the Eickbush Lab at the University of Rochester aiding graduate students in acquiring and analyzing large data sets from online sequencing databases. He was so successful that he eventually became a permanent fixture in the lab. Over time, his focus shifted from data mining to taking over a project involving simulating how transposable elements can maintain themselves in the genome over long periods of time.
Seeking to expand his scientific experience, Michael took the opportunity to head to Seattle for a change of scenery and join the Malik Lab at Fred Hutchinson Cancer Research Center. While there, he worked with several post-docs on various projects studying genetic conflict in a variety of model organisms including viruses, yeast, and mice. This was where he first met Sarah and worked with her for a number of years on meiotic drive in fission yeast. He found the project so fascinating, that when Sarah offered him a position in her new lab in Kansas City, and the fact that Stowers has a core facility for media prep that would free him from pouring thousands of plates for her, he decided to accept.
In summer, when not in the lab, Michael can usually be found outdoors hiking trails or walking the neighborhood. When the weather grows colder, he takes to the ice with his broom for the sport of curling and was quite pleased to find that Kansas City has a club. To the enjoyment of the rest of the lab, Michael is also an avid baker, possessing no small amount of skill. This can prove problematic with other lab members pestering him to bring in more goodies.
wtf genes are prolific dual poison-antidote meiotic driver
Nuckolls N.L., Bravo Núñez M.A., Eickbush M.T., Young J.M., Lange J.J., Yu J.S., Smith G.R., Jaspersen S.L., Malik H.S., Zanders S.E. eLife
Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast.
Zanders S, Eickbush MT, Yu JS, Kang JW, Fowler KR, Smith GR, Malik HS. eLife
A population genetic model for the maintenance of R2 retrotransposons in rRNA gene loci.
Zhou J., Eickbush M.T., Eickbush T.H. (2013) PLoS Genetics
Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses.
Elde N.C., Child S.J., Eickbush M.T., Kitzman J.O., Shendure J., Geballe A.P., Malik H.S. (2012) Cell
Retrotransposition of R2 elements in somatic nuclei during the early development of Drosophila.
Eickbush M.T., Eickbush T.H. (2011) Mobile DNA
. 2(1): 11
Role of recombination in the long-term retention of transposable elements in rRNA gene loci.
Zhang X., Eickbush M.T., Eickbush T.H. (2008) Genetics
. 180(3): 1617-26